Human Developmental Biology Resource (HDBR)

News & Publications

Neurodevelopmental protein Musashi-1 interacts with the Zika genome and promotes viral replication

Neurodevelopmental protein Musashi-1 interacts with the Zika genome and promotes viral replication - Read more

July 7, 2017

Kisspeptin Is a Novel Regulator of Human Fetal Adrenocortical Development and Function: A Finding With Important Implications for the Human Fetoplacental Unit.

Kisspeptin is a novel regulator of human fetal adrenocortical development and function – a finding with important implications for the human feto-placental unit
  - Read more

June 21, 2017

Integrated genome and transcriptome sequencing identifies a noncoding mutation in the genome replication factor DONSON as the cause of microcephaly-micromelia syndrome.

Integrated genome and transcriptome sequencing identifies a noncoding mutation in the genome replication factor DONSON as the cause of microcephaly-micromelia syndrome. - Read more

June 19, 2017

Distinct cortical and sub-cortical neurogenic domains for GABAergic interneuron precursor transcription factors NKX2.1, OLIG2

Distinct cortical and sub-cortical neurogenic domainsfor GABAergic interneuron precursor transcription factorsNKX2.1, OLIG2 - Read more

March 16, 2017

Genome-Wide Significant Schizophrenia Risk Variation on Chromosome 10q24 Is Associated With Altered cis-Regulation of BORCS7, AS3MT, and NT5C2 in the Human Brain

Genome-Wide Significant Schizophrenia RiskVariation on Chromosome 10q24 Is AssociatedWith Altered cis-Regulation of BORCS7, AS3MT, andNT5C2 in the Human Brain - Read more

March 16, 2017

Enhancer Variants Synergistically Drive Dysfunction of a Gene Regulatory Network In Hirschsprung Disease

Enhancer Variants Synergistically Drive Dysfunctionof a Gene Regulatory Network In HirschsprungDisease - Read more

March 16, 2017

Zika Virus Disrupts Phospho-TBK1 Localization and Mitosis in Human Neuroepithelial Stem Cells and Radial Glia.

Zika Virus Disrupts Phospho-TBK1 Localization and Mitosis in Human Neuroepithelial Stem Cells and Radial Glia. - Read more

March 16, 2017

Methylation quantitative trait loci in the developing brain and their enrichment in schizophrenia-associated genomic regions

Methylation quantitative trait loci in the developing brain and their enrichment in schizophrenia-associated genomic regions  - Read more

March 16, 2017

In vivo transplantation of fetal human gut‐derived enteric neural crest cells

In vivo transplantation of fetal human gut‐derived enteric neural crest cells - Read more

January 29, 2017

Three-dimensional arrangement of elastic fibers in the human corneal stroma

Three-dimensional arrangement of elastic fibers in the human corneal stroma.Lewis PN, White TL, Young RD, Bell JS, Winlove CP, Meek KM. - Read more

April 5, 2016

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